Federica
Wed Oct 30 2024
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5 answers
1208
What is STAT1 STAT3 gain of function and mechanisms of immune dysregulation?
STAT1 and STAT3 are members of the STAT family of transcription factors. Gain-of-function mutations in these genes lead to immune dysregulation by altering their normal regulatory roles. Specifically, such mutations can result in enhanced or abnormal activation of immune responses, contributing to the development of immune-related diseases.
